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Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs.

Grant (non-repayable) Open now

Funder

National Institutes of Health
Funder profile and all of its programs

Amount

Up to $3,000,000 per award (published on Grants.gov).

Where

United States (federal)

Eligibility

Open to businesses, self-employed people, nonprofits, colleges, universities, schools or research institutions and state, provincial, local or tribal governments. No cost sharing is required.

Sectors

Education and training, Health and life sciences, Nonprofits and charities, Research and science

Deadline

Closes 21 August 2028

Source

Grants.gov XML extract (PAR-25-446)

Last checked

2 November 2026

Funder contacts

Public organizational contacts on file Unlock full profile / Sign up

Official page ↗

From official open data: listed in the official Grants.gov extract on 2026-11-02. The summary is from the official listing; the eligibility line is our plain-language reading of its eligibility codes. Confirm details on the official page.

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Education and training Health and life sciences Nonprofits and charities Governments and public bodies Schools, colleges and research institutions Nonprofits and charities United States United States (national) Federal agency $1 million or more August 2028

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